Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine - Springer
نویسندگان
چکیده
Male Wistar rats received 340 mg/kg of either unformulated curcumin or curcumin formulated with phosphatidylcholine (Meriva) by oral gavage. Rats were killed at 15, 30, 60 and 120 min post administration. Plasma, intestinal mucosa and liver were analysed for the presence of curcumin and metabolites using HPLC with UV detection. Identity of curcumin and metabolites was verified by negative ion electrospray liquid chromatography/tandem mass spectrometry. Comparison of systemic availability of curcumin with that o... http://link.springer.com/article/10.1007/s00280-006-0355-...
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